World-wide sensor web generates tremendous amount of sensor data stream allowing people to observe events that were previously unobservable.Sensor web has been wildly applied in many monitoring systems; some of them are extremely time-sensitive, e.g., disaster management systems.However, with the growing amount of sensor data, the traditional reque

Manuela De Gregori,1–3 Carolina Muscoli,2,4,5 Michael E Schatman,2,6 Tiziana Stallone,2,7 Fabio Intelligente,2,8 Mariangela Rondanelli,2,9 Francesco Franceschi,2,10 Laura Isabel Arranz,2,11 Silvia Lorente-Cebrián,2,12 Maurizio Salamone,2,13,14 Sara Ilari,2,5 Inna Belfer,2,15 Massimo Allegri2,16,17 1Pain Therapy Service, Fondazione IRCC

The ERK5 cascade is a MAPK pathway that transmits both Bedding mitogenic and stress signals, yet its mechanism of activation is not fully understood.Using intracellular calcium modifiers, we found that ERK5 activation by EGF is inhibited both by the depletion and elevation of intracellular calcium levels.This calcium effect was found to occur upstr

Arminiye as one of the most important parts of the Caucasus region and because of being on the Silk Road and the borders of the Islamic world with Dar-alKufr, has always played a significant role in the history of this area has changes.Despite weakness due to lack of documents and statistics on Islamic historiography has always been one of the majo

Abstract Background Allostery is one of the most powerful and common ways of regulation of protein activity.However, for most allosteric proteins identified to date the mechanistic details of allosteric modulation are not yet well understood.Uncovering common mechanistic patterns underlying allostery would allow not only a better academic understan